InterPro domain: IPR025287

Wall-associated kinases (WAKs) are transmembrane proteins containing a cytoplasmic serine/threonine kinase domain and an extracellular domain in contact with the pectin fraction of the plant cell wall [ 1 ]. The cysteine-rich galacturonan-binding domain is located near the N-terminal end of the extracellular domain and binds to the cell-wall pectins [ 2 , 3 ].

1. A cluster of five cell wall-associated receptor kinase genes, Wak1-5, are expressed in specific organs of Arabidopsis. Plant Mol. Biol. 39, 1189-96
2. Wall-associated kinase WAK1 interacts with cell wall pectins in a calcium-induced conformation. Plant Cell Physiol. 46, 268-78
3. In vitro characterization of the homogalacturonan-binding domain of the wall-associated kinase WAK1 using site-directed mutagenesis. Phytochemistry 67, 1068-79