InterPro domain: IPR024709

This entry represents a group of plant-specific O-fucosyltransferases and their homologues [ 1 ]. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes [ 2 , 3 ].

1. Plant Glycosyltransferases Beyond CAZy: A Perspective on DUF Families. Front Plant Sci 3, 59
2. A new superfamily of protein-O-fucosyltransferases, alpha2-fucosyltransferases, and alpha6-fucosyltransferases: phylogeny and identification of conserved peptide motifs. Glycobiology 13, 1C-5C
3. The fucosyltransferase gene family: an amazing summary of the underlying mechanisms of gene evolution. Genetica 118, 157-70