InterPro domain: IPR024706

Peroxiredoxins are a family of ubiquitous proteins found in all kingdoms of life. They are important for antioxidant defence and, in eukaryotes, participate in redox signalling [ 1 ].

This family includes alkyl hydroperoxide reductase subunit C (AphC) from bacteria [ 2 ], and peroxiredoxins 1 (PRDX1), 2 (PRDX2), 4 (PRDX4) and 6 (PRDX6).

1. Structure-based Insights into the Catalytic Power and Conformational Dexterity of Peroxiredoxins. Antioxid. Redox Signal. 15, 795-815
2. Catalase (KatA) and alkyl hydroperoxide reductase (AhpC) have compensatory roles in peroxide stress resistance and are required for survival, persistence, and nasal colonization in Staphylococcus aureus. J. Bacteriol. 189, 1025-35