InterPro domain: IPR024678

General Information

  • Identifier IPR024678
  • Description Serine/threonine-protein kinase OSR1/WNK, CCT domain
  • Number of genes 489
  • Gene duplication stats Loading...
  • Associated GO terms GO:0005524   GO:0004674  

Abstract

Oxidative-stress-responsive kinase 1 (OSR1) is involved in the signalling cascade which activates Na/K/2Cl co-transporter during osmotic stress. This entry represents the CCT domain found in OSR1, STE20/SPS1-related kinase and in WNK activators [ 1 ]. This domain is found in eukaryotes, and is approximately 40 amino acids in length. There is a single completely conserved residue F that may be functionally important.


1. Structural insights into the recognition of substrates and activators by the OSR1 kinase. EMBO Rep. 8, 839-45

Species distribution

Gene table