InterPro domain: IPR024585
General Information
- Identifier IPR024585
- Description Domain of unknown function DUF3385, target of rapamycin protein
- Number of genes 136
- Gene duplication stats Loading...
Abstract
This uncharacterised domain is is typically between 160 to 172 amino acids in length. It is found in the phosphatidylinositol kinase-related protein kinases TOR (target of rapamycin). In Saccharomyces cerevisiae the TOR proteins, TOR1 and TOR2, regulate growth in a rapamycin-sensitive manner [ 1 ].
1. Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol. Cell 10, 457-68
Species distribution
Gene table
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