InterPro domain: IPR024530

This is a family of short Pseudomonas proteins that are potential virulence factors. The structure of Q9HY15 a secreted protein has been solved and deposited as PDB:3npd, from Pfam:PF13652. It is predicted that these two adjacent proteins form a single transcriptional unit based on the prediction that together they interact with their adjacent protein PotD, which is the putrescine-binding periplasmic protein in the polyamine uptake system comprising PotABCD. These two adjacent proteins are predicted to be quroum-sensing-regulated virulence factors [ 1 ].

1. Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family. Proteins 82, 1086-92