InterPro domain: IPR024260
General Information
- Identifier IPR024260
- Description Vacuolar segregation subunit 7
- Number of genes 1
- Gene duplication stats Loading...
Abstract
Vac7 is localised at the vacuole membrane, a location which is consistent with its involvement in vacuole morphology and inheritance [ 1 ]. Vac7 has been shown to function as an upstream regulator of the Fab1 lipid kinase pathway [ 2 ]. The Fab1 lipid pathway is important for correct regulation of membrane trafficking events.
1. Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology. Mol. Cell. Biol. 17, 6847-58
2. Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member. Mol. Biol. Cell 13, 1238-51
Species distribution
Gene table
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