InterPro domain: IPR024224
General Information
- Identifier IPR024224
- Description DENND6
- Number of genes 124
- Gene duplication stats Loading...
- Associated GO terms GO:0005085
Abstract
The DENND6 family of proteins includes DENND6A and B. They act as guanine nucleotide exchange factors (GEF) for RAB14 [ 1 ].
1. Rab14 and its exchange factor FAM116 link endocytic recycling and adherens junction stability in migrating cells. Dev. Cell 22, 952-66
Species distribution
Gene table
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