InterPro domain: IPR023476

General Information

  • Identifier IPR023476
  • Description Peptidyl-tRNA hydrolase II domain superfamily
  • Number of genes 360
  • Gene duplication stats Loading...

Abstract

Peptidyl-tRNA hydrolases are enzymes that release tRNAs from peptidyl-tRNA during translation [ 1 ].

This superfamily represents the structural domain found in these t-RNA hydrolases and which form dimers [ 2 ].


1. Orthologs of a novel archaeal and of the bacterial peptidyl-tRNA hydrolase are nonessential in yeast. Proc. Natl. Acad. Sci. U.S.A. 99, 16707-12
2. Crystal structure at 1.8 A resolution and identification of active site residues of Sulfolobus solfataricus peptidyl-tRNA hydrolase. Biochemistry 44, 4294-301

Species distribution

Gene table