InterPro domain: IPR022677

General Information

  • Identifier IPR022677
  • Description Myristoyl-CoA:protein N-myristoyltransferase, C-terminal
  • Number of genes 230
  • Gene duplication stats Loading...
  • Associated GO terms GO:0004379  

Abstract

Myristoyl-CoA:protein N-myristoyltransferase ( 2.3.1.97 ) (Nmt) [ 1 ] is the enzyme responsible for transferring a myristate group on the N-terminal glycine of a number of cellular eukaryotics and viral proteins. Nmt is a monomeric protein of about 50 to 60kDa whose sequence appears to be well conserved.

The N and C-terminal domains of NMT are structurally similar, each adopting an acyl-CoA N-acyltransferase-like fold. This entry represents the C-terminal region.


1. MyristoylCoA:protein N-myristoyltransferase. Adv. Enzymol. Relat. Areas Mol. Biol. 67, 375-430

Species distribution

Gene table