InterPro domain: IPR022192

General Information

  • Identifier IPR022192
  • Description Mitochondrial degradasome RNA helicase subunit, C-terminal domain
  • Number of genes 227
  • Gene duplication stats Loading...
  • Associated GO terms GO:0016817  

Abstract

This domain is found in ATP-dependent RNA helicase SUV3. It is found in bacterial and eukaryotic proteins, it is approximately 50 amino acids in length and it is usually found in association with PF00271 .

The yeast mitochondrial degradosome (mtEXO) is an NTP-dependent exoribonuclease involved in mitochondrial RNA metabolism. mtEXO is made up of two subunits: an RNase (DSS1) and an RNA helicase (SUV3). These co-purify with mitochondrial ribosomes [ 1 ].


1. The yeast mitochondrial degradosome. Its composition, interplay between RNA helicase and RNase activities and the role in mitochondrial RNA metabolism. J. Biol. Chem. 278, 1603-11

Species distribution

Gene table