InterPro domain: IPR022051

This entry represents a group of proteins mostly from plants and Cyanobacteria (blue-green algae), including TIC21 from Arabidopsis. TIC21 is Involved in chloroplast protein import across the inner envelope membrane. It can acts as a chloroplast permease regulating the iron transport and homeostasis [ 1 , 2 ].

1. PIC1, an ancient permease in Arabidopsis chloroplasts, mediates iron transport. Plant Cell 19, 986-1006
2. The chloroplast permease PIC1 regulates plant growth and development by directing homeostasis and transport of iron. Plant Physiol. 155, 1709-22