InterPro domain: IPR021933

This domain can be found in the N terminus of the SERRATE (SE) from plants and its homologue, Ars2, from animals. They play a role in nuclear RNA metabolism. They interact with the nuclear cap-binding complex (CBC) and mediates interactions with diverse RNA processing and transport machineries in a transcript-dependent manner. Interestingly, the plant SERRATE does not have the RNA recognition motif (RRM) domain found in metazoans and S. pombe [ 1 ].

1. Structural analysis of human ARS2 as a platform for co-transcriptional RNA sorting. Nat Commun 9, 1701