InterPro domain: IPR021914
General Information
- Identifier IPR021914
- Description Transcriptional factor DELLA, N-terminal
- Number of genes 356
- Gene duplication stats Loading...
Abstract
Gibberellins are plant hormones which have great impact on growth signalling. DELLA proteins are transcriptional regulators of growth related proteins that lack a DNA binding domain and exert its negative regulation of gibberellin responses through interaction with other transcription factors [ 1 ]. DELLAs are downregulated when gibberellins bind to their receptor GID1 [ 2 , 2 ], which forms a complex with DELLA proteins and signals them towards 26S proteasome. The N-terminal of DELLA proteins contains conserved DELLA and TVHYNP motifs which are important for GID1 binding and proteolysis of the DELLA proteins [ 3 , 3 ].
1. Arabidopsis DELLA and two HD-ZIP transcription factors regulate GA signaling in the epidermis through the L1 box cis-element. Plant Cell 26, 2905-19
2. Gibberellin-induced DELLA recognition by the gibberellin receptor GID1. Nature 456, 459-63
3. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell 26, 2920-38