InterPro domain: IPR021846

General Information

  • Identifier IPR021846
  • Description NFACT protein, C-terminal
  • Number of genes 114
  • Gene duplication stats Loading...

Abstract

This is the C-terminal domain of the NFACT (NEMF, FbpA, Caliban, and Tae2) proteins involved in the ribosomal quality control pathway. This context is conserved in archaea and eukaryotes, but NFACT proteins in bacteria lack the NFACT-C domain [ 1 ].


1. A highly conserved family of domains related to the DNA-glycosylase fold helps predict multiple novel pathways for RNA modifications. RNA Biol 11, 360-72

Species distribution

Gene table