InterPro domain: IPR021793

Oprl is a major outer membrane lipoprotein that contains an alanine-zipper [ 1 , 2 ]. Zipper motifs are a seven-repeat motif where the first and fourth positions are occupied by an aliphatic residue, usually a leucine. These residues are positioned on the outside of the coil such as to bind firmly to one or more monomers of the protein to create a triple or five-helical coiled-coil that probably forms a seam in a membrane.

1. Cloning and analysis of the gene for the major outer membrane lipoprotein from Pseudomonas aeruginosa. Mol. Microbiol. 3, 421-8
2. Pseudomonas aeruginosa outer membrane lipoprotein I gene: molecular cloning, sequence, and expression in Escherichia coli. J. Bacteriol. 171, 4130-7