InterPro domain: IPR021261

Proteins in this family include glycerophosphocholine acyltransferase 1 (GPCAT). GPCAT homologues have been identified in most eukaryotes except chordates, but are not found in prokaryotes. GPCAT can acylate glycero-3-phosphocholine (GPC) with acyl groups from acyl-CoA. Thus it contributes to the maintenance of phosphatidylcholine (PC) homeostasis and may have specific functions in acyl editing of PC [ 1 ].

1. Cloning of Glycerophosphocholine Acyltransferase (GPCAT) from Fungi and Plants: A NOVEL ENZYME IN PHOSPHATIDYLCHOLINE SYNTHESIS. J. Biol. Chem. 291, 25066-25076