InterPro domain: IPR021198
General Information
- Identifier IPR021198
- Description Pyridoxamine 5'-phosphate oxidase, plant
- Number of genes 6
- Gene duplication stats Loading...
- Associated GO terms GO:0004733 GO:0008615 GO:0052856 GO:0052857
Abstract
This entry represents plant-specific pyridoxine/pyridoxamine 5'-phosphate oxidase 1 (PPOX1 or PDX3) [ 1 ]. It is involved in the salvage pathway of pyridoxal 5'-phosphate (vitamin B6) [ 2 ].
It may also also catalyse the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration [ 3 ].
1. Identification of a pyridoxine (pyridoxamine) 5'-phosphate oxidase from Arabidopsis thaliana. FEBS Lett. 581, 344-8
2. Vitamer levels, stress response, enzyme activity, and gene regulation of Arabidopsis lines mutant in the pyridoxine/pyridoxamine 5'-phosphate oxidase (PDX3) and the pyridoxal kinase (SOS4) genes involved in the vitamin B6 salvage pathway. Plant Physiol. 145, 985-96
3. Plants utilize a highly conserved system for repair of NADH and NADPH hydrates. Plant Physiol. 165, 52-61