InterPro domain: IPR020971
General Information
- Identifier IPR020971
- Description ATP synthase, F1 beta subunit
- Number of genes 217
- Gene duplication stats Loading...
- Associated GO terms GO:0016887 GO:0005524 GO:0000275 GO:0006754
Abstract
F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c. This entry represents the beta subunit of the F1 component.
The NMR solution structure of the protein in SDS micelles was found to contain two helices, an N-terminal amphipathic alpha-helix and a C-terminal alpha-helix separated by a large unstructured internal domain. The N-terminal alpha-helix is the Tom20 receptor binding site whereas the C-terminal alpha-helix is located upstream of the mitochondrial processing peptidase cleavage site [ 1 ].
1. NMR solution structure of the mitochondrial F1beta presequence from Nicotiana plumbaginifolia. J. Mol. Biol. 336, 1129-40