InterPro domain: IPR019999

This entry represents the anthranilate synthase component 1 protein 4.1.3.27 and its homologues, including aminodeoxychorismate synthase component 1 2.6.1.85 , 2-amino-4-deoxychorismate synthase 2.6.1.86 and isochorismate synthase/isochorismate-pyruvate lyase MbtI 5.4.4.2 .

Anthranilate synthase component 1 is a tetramer comprising two copies of component I and two copies of component II. Component I catalyses the formation of anthranilate using ammonia rather than glutamine, while component II provides glutamine amidotransferase activity.