InterPro domain: IPR019991

This entry represents a family GTP-binding proteins involved in ribosome biogenesis, typified by the essential Bacillus subtilis protein YlqF [ 1 ]. They are related to Era, EngA, and other GTPases involved in ribosome biogenesis, but are circularly permuted. This family is not universal, and is not present in Escherichia coli, so it is not as well studied as some other GTPases.

1. Isolation and characterization of a dominant negative mutant of Bacillus subtilis GTP-binding protein, YlqF, essential for biogenesis and maintenance of the 50 S ribosomal subunit. J. Biol. Chem. 282, 25270-7