InterPro domain: IPR019595

This entry represents an uncharacterised domain that can be found in a group of putative haem-iron utilisation proteins. It can also be found in C-terminal of the glutamyl-tRNA reductase-binding (GluTRBP) protein from Arabidopsis [ 1 ]. GluTRBP is involved in the regulation of glutamyl-tRNA reductase (GluTR) which is important for the synthesis and distribution of 5-aminolevulinate, a precursor in heme and chlorophyll biosynthesis [ 2 ]. GluTRBP is necessary for efficient photosynthetic electron transport in chloroplasts [ 3 ].

1. Crystal structure of Arabidopsis glutamyl-tRNA reductase in complex with its stimulator protein. Proc. Natl. Acad. Sci. U.S.A. 111, 6630-5
2. An Arabidopsis GluTR binding protein mediates spatial separation of 5-aminolevulinic acid synthesis in chloroplasts. Plant Cell 23, 4476-91
3. Arabidopsis thaliana PGR7 encodes a conserved chloroplast protein that is necessary for efficient photosynthetic electron transport. PLoS ONE 5, e11688