InterPro domain: IPR019377

General Information

  • Identifier IPR019377
  • Description NADH-ubiquinone oxidoreductase, subunit 10
  • Number of genes 82
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Abstract

NADH-ubiquinone oxidoreductase subunit 10 of (NDUFB10) is a member of a family of conserved proteins of up to 180 residues. It is one of the 41 protein subunits within the hydrophobic fraction of the NADH:ubiquinone oxidoreductase (complex I), a multiprotein complex located in the inner mitochondrial membrane whose main function is the transport of electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. NDUFB10 is encoded in the nucleus [ 1 , 2 ].


1. Accessory subunits are integral for assembly and function of human mitochondrial complex I. Nature 538, 123-126
2. The nuclear encoded subunits of complex I from bovine heart mitochondria. Biochim. Biophys. Acta 1604, 135-50

Species distribution

Gene table

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