InterPro domain: IPR019164

General Information

  • Identifier IPR019164
  • Description Transmembrane protein 147
  • Number of genes 142
  • Gene duplication stats Loading...

Abstract

TMEM147 is a component of the Nicalin-NOMO protein complex, which catalyzes the proteolytic cleavage of the transmembrane domain of various proteins including the beta-amyloid precursor protein and Notch [ 1 ].


1. Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex. J. Biol. Chem. 285, 26174-81

Species distribution

Gene table