InterPro domain: IPR019144

Membralin is evolutionarily highly conserved, though it appears to represent a unique protein family. The protein appears to contain several transmembrane regions. In humans it is expressed in certain cancers, particularly ovarian cancers [ 1 ]. Membralin-like gene homologues have been identified in plants including grape, cotton and tomato [ 2 ].

1. Identification and characterization of membralin, a novel tumor-associated gene, in ovarian carcinoma. Biochim. Biophys. Acta 1730, 96-102
2. Characterization and expression of the gene encoding membralin, an evolutionary conserved protein expressed in the central nervous system. Brain Res. Gene Expr. Patterns 1, 205-12