InterPro domain: IPR019084

This domain is found at the N-terminal region of the Stm1 and similar proteins. Stm1 is a G4 quadraplex and purine motif triplex nucleic acid-binding protein. It has been implicated in many biological processes including apoptosis and telomere biosynthesis. Stm1 is known to interact with Cdc13 [ 1 ], and is known to associate with ribosomes and nuclear telomere cap complexes [ 2 ]. This domain is also found at the N-terminal of some 'RGG repeats nuclear RNA binding proteins' [ 3 ].

1. STM1, a gene which encodes a guanine quadruplex binding protein, interacts with CDC13 in Saccharomyces cerevisiae. Mol. Genet. Genomics 267, 806-13
2. Stm1p, a G4 quadruplex and purine motif triplex nucleic acid-binding protein, interacts with ribosomes and subtelomeric Y' DNA in Saccharomyces cerevisiae. J. Biol. Chem. 279, 24323-33
3. The Arabidopsis RNA-binding protein AtRGGA regulates tolerance to salt and drought stress. Plant Physiol. 168, 292-306