InterPro domain: IPR018993

General Information

  • Identifier IPR018993
  • Description FGFR1 oncogene partner (FOP), N-terminal dimerisation domain
  • Number of genes 8
  • Gene duplication stats Loading...
  • Associated GO terms GO:0034453   GO:0005815  

Abstract

Fibroblast growth factor receptor 1 (FGFR1) oncogene partner (FOP) is a centrosomal protein that is involved in anchoring microtubules to centrosomes. This domain includes a Lis-homology motif. It forms an alpha-helical bundle and is involved in dimerisation [ 1 ].


1. Structure of the N-terminal domain of the FOP (FGFR1OP) protein and implications for its dimerization and centrosomal localization. J. Mol. Biol. 359, 863-75

Species distribution

Gene table