InterPro domain: IPR018844
General Information
- Identifier IPR018844
- Description Nucleolar protein Dnt1-like, N-terminal
- Number of genes 1
- Gene duplication stats Loading...
Abstract
Cytokinesis in yeasts involves a family of proteins whose essential function is to bind Cdc14-family phosphatase and prevent this from being sequestered and inhibited in the nucleolus. This is the highly conserved N terminus of a family of proteins which act as cytokinesis checkpoint controls by allowing cells to cope with cytokinesis defects. These proteins are required for rDNA silencing and mini-chromosome maintenance [ 1 ].
1. The nucleolar Net1/Cfi1-related protein Dnt1 antagonizes the septation initiation network in fission yeast. Mol. Biol. Cell 18, 2924-34
Species distribution
Gene table
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