InterPro domain: IPR017824
General Information
- Identifier IPR017824
- Description Aminodeoxychorismate lyase, class IV
- Number of genes 54
- Gene duplication stats Loading...
- Associated GO terms GO:0030170 GO:0046656 GO:0008696
Abstract
Aminodeoxychorismate lyase (ADC lyase) converts aminodeoxychorismate to para-aminobenzoate during the process of tetrahydrofolate biosynthesis [ 1 ]. Tetrahydrofolate is an essential precursor for de novo purine biosynthesis. ADC lyase is a pyridoxal-phosphate-binding protein belonging to the class IV aminotransferase family.
1. Characterization and sequence of Escherichia coli pabC, the gene encoding aminodeoxychorismate lyase, a pyridoxal phosphate-containing enzyme. J. Bacteriol. 174, 5317-23
Species distribution
Gene table
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