InterPro domain: IPR017416
General Information
- Identifier IPR017416
- Description Chaperonin Cpn20
- Number of genes 186
- Gene duplication stats Loading...
- Associated GO terms GO:0046914 GO:1901671 GO:0006457
Abstract
Cpn20 is a functional homologue of the cpn10 (also known as GroES) co-chaperonin, but it consists of two cpn10-like units joined head-to-tail by a short chain of amino acids. This double protein is unique to plastids and was shown to exist in plants as well plastid-containing parasites [ 1 ]. Cpn20 seems to function as a co-chaperone, along with cpn60, and in certain cases is essential for the discharge of biologically active proteins from cpn60 [ 2 ]. It might be an iron chaperone for superoxide dismutase in activating iron superoxide dismutase (FeSOD) [ 3 ].
1. Cpn20: siamese twins of the chaperonin world. Plant Mol. Biol. 69, 227-38
2. CHAPERONIN 20 mediates iron superoxide dismutase (FeSOD) activity independent of its co-chaperonin role in Arabidopsis chloroplasts. New Phytol. 197, 99-110
3. Chaperonin 20 might be an iron chaperone for superoxide dismutase in activating iron superoxide dismutase (FeSOD). Plant Signal Behav 8, e23074