InterPro domain: IPR017375

General Information

  • Identifier IPR017375
  • Description Peroxisome assembly protein 12

Abstract

This group represents peroxisome assembly protein 12, also known as Peroxin-12 or PEX12. PEX12 is required for protein import into peroxisomes [ 1 , 2 ].


1. PEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of PEX12p. Mol. Cell. Biol. 18, 4324-36
2. PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import. J. Cell Biol. 147, 761-74

Species distribution

Gene table