InterPro domain: IPR017364
General Information
- Identifier IPR017364
- Description Gem-associated protein 2
- Number of genes 8
- Gene duplication stats Loading...
- Associated GO terms GO:0005681 GO:0000245 GO:0000387
Abstract
This entry represents Gem-associated protein 2 (GEMIN2, also known as SIP1). GEMIN2 is part of the SMN complex, which plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus [ 1 ].
1. The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell 90, 1013-21
Species distribution
Gene table
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