InterPro domain: IPR017117

General Information

  • Identifier IPR017117
  • Description Ribonuclease Nob1, eukaryote

Abstract

Budding yeast Nob1 is involved in proteasomal and 40S ribosomal subunit biogenesis. It is required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA [ 1 , 2 , 3 ].


1. Nob1p, a new essential protein, associates with the 26S proteasome of growing saccharomyces cerevisiae cells. Gene 243, 37-45
2. Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits. Nat. Struct. Mol. Biol. 19, 744-53
3. Nob1p is required for cleavage of the 3' end of 18S rRNA. Mol. Cell. Biol. 23, 1798-807

Species distribution

Gene table