InterPro domain: IPR017046

General Information

  • Identifier IPR017046
  • Description Prenylcysteine oxidase
  • Number of genes 140
  • Gene duplication stats Loading...
  • Associated GO terms GO:0001735  

Abstract

This entry represents a characterised prenylcysteine oxidase (originally thought to be a prenylcysteine lyase) and homologues that are predicted to have the same function. The human enzyme is part of the lysosome and functions in the degradation of prenylated proteins, cleaving the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine [ 1 ].


1. Cloning, expression, and cellular localization of a human prenylcysteine lyase. J. Biol. Chem. 274, 35802-8

Species distribution

Gene table

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