InterPro domain: IPR016833

General Information

  • Identifier IPR016833
  • Description Putative sodium bile acid cotransporter
  • Number of genes 156
  • Gene duplication stats Loading...

Abstract

This family includes sodium/bile acid cotransporter 7 [ 1 ] and other uncharacterised proteins with sodium bile acid cotransporter domain; they are found both in prokaryotes and eukaryotes.They are related to the human bile acid:sodium symporters, which are transmembrane proteins functioning in the liver in the uptake of bile acids from portal blood plasma, a process mediated by the co-transport of Na + [ 2 ].


1. Molecular cloning and characterization of a novel human C4orf13 gene, tentatively a member of the sodium bile acid cotransporter family. Biochem. Genet. 43, 165-73
2. Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system. Proc. Natl. Acad. Sci. U.S.A. 88, 10629-33

Species distribution

Gene table

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