InterPro domain: IPR016696

TRS31 (also known as TRAPPC5) is a subunit of the trafficking protein particle complex (TRAPP). It is one of the six core subunits of TRAPP complexes which play a key role in the regulation of ER-to-Golgi and intra-Golgi transport by tethering the vesicle membrane to the target membrane [ 1 , 2 , 3 , 4 , 5 ].

1. The architecture of the multisubunit TRAPP I complex suggests a model for vesicle tethering. Cell 127, 817-30
2. A trapper keeper for TRAPP, its structures and functions. Cell. Mol. Life Sci. 69, 3933-44
3. The TRAPP complex: insights into its architecture and function. Traffic 9, 2032-42
4. TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion. EMBO J. 17, 2494-503
5. TRAPP complexes in membrane traffic: convergence through a common Rab. Nat. Rev. Mol. Cell Biol. 11, 759-63