InterPro domain: IPR016478

This group represents GTPases that belong to MMR1/HSR1 GTP-binding protein family, MTG1 subfamily. This entry includes Mitochondrial GTPase MTG1 which is required for mitochondrial translation. It is probably involved in assembly of the large ribosomal subunit [ 1 ]. This family also includes Ribosome biogenesis GTPase A, an essential protein for a late step of 50S ribosomal subunit assembly [ 2 , 3 ].

1. MTG1 codes for a conserved protein required for mitochondrial translation. Mol. Biol. Cell 14, 2292-302
2. The essential GTPase RbgA (YlqF) is required for 50S ribosome assembly in Bacillus subtilis. Mol. Microbiol. 59, 528-40
3. Isolation and characterization of a dominant negative mutant of Bacillus subtilis GTP-binding protein, YlqF, essential for biogenesis and maintenance of the 50 S ribosomal subunit. J. Biol. Chem. 282, 25270-7