InterPro domain: IPR016089

General Information

  • Identifier IPR016089
  • Description Chalcone isomerase, orthogonal bundle domain superfamily
  • Number of genes 681
  • Gene duplication stats Loading...

Abstract

Chalcone isomerase ( 5.5.1.6 ; also known as chalcone-flavanone isomerase or fatty-acid-binding protein) is a plant enzyme responsible for the isomerisation of chalcone to naringenin, a key step in the biosynthesis of flavonoids. The Petunia hybrida (Petunia) genome contains two genes coding for very similar enzymes, ChiA and ChiB, but only the first seems to encode a functional chalcone isomerase. This superfamily represents an alpha-helical orthogonal bundle subdomain found in chalcone isomerases [ 1 ].


1. Structure and mechanism of the evolutionarily unique plant enzyme chalcone isomerase. Nat. Struct. Biol. 7, 786-91

Species distribution

Gene table

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