InterPro domain: IPR016020
General Information
- Identifier IPR016020
- Description Translation initiation factor 3, subunit 12, N-terminal, eukaryotic
- Number of genes 134
- Gene duplication stats Loading...
- Associated GO terms GO:0003743 GO:0043022 GO:0006446 GO:0005852
Abstract
This superfamily represents the N-terminal domain found in several eukaryotic translation initiation factor 3 subunit 12 (eIF-3 p25; also known as subunit K) proteins. Eukaryotic initiation factor 3 (eIF3) is a multi-subunit complex that is required for binding of mRNA to 40S ribosomal subunits, stabilisation of ternary complex binding to 40S subunits, and dissociation of 40S and 60S subunits [ 1 ].
1. Plant initiation factor 3 subunit composition resembles mammalian initiation factor 3 and has a novel subunit. J. Biol. Chem. 276, 2122-31
Species distribution
Gene table
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