InterPro domain: IPR015359

General Information

  • Identifier IPR015359
  • Description Phosphoinositide-specific phospholipase C, EF-hand-like domain
  • Number of genes 406
  • Gene duplication stats Loading...

Abstract

This domain is predominantly found in the enzyme phosphoinositol-specific phospholipase C. It adopts a structure consisting of a core of four alpha helices, in an EF like fold, and is required for functioning of the enzyme [ 1 ].


1. C2 domain conformational changes in phospholipase C-delta 1. Nat. Struct. Biol. 3, 788-95

Species distribution

Gene table