InterPro domain: IPR014612

This entry includes fission yeast ribonucleases P/MRP protein subunit Pop7 and its homologue, Rpp20, from animals. Pop7/Rpp20 is a component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. They are also a component of RNase MRP complex, which cleaves pre-rRNA sequences [ 1 , 2 ].

1. Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex. Nucleic Acids Res. 32, 2138-46
2. RNA binding properties of conserved protein subunits of human RNase P. Nucleic Acids Res. 39, 5704-14