InterPro domain: IPR014002
General Information
- Identifier IPR014002
- Description Agenet domain, plant type
- Number of genes 2283
- Gene duplication stats Loading...
Abstract
This entry represents an agenet domain found in EMSY-like (AtEML) proteins, which have possible roles in chromatin regulation and are related to the BRCA2-interacting human oncoprotein EMSY [ 1 ]. Proteins containing this domain also include MRG2 (AT1G02740) from Arabidopsis and PHD finger protein 20-like protein 1 (PHF20L1) from animals. MRG2 binds to the FLOWERING LOCUS T locus and elevates the expression in an H3K36me3-dependent manner [ 2 ]. The function of PHF20L1 is not clear.
1. EMSY-like genes are required for full RPP7-mediated race-specific immunity and basal defense in Arabidopsis. Mol. Plant Microbe Interact. 24, 1573-81
2. Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes. Nucleic Acids Res. 42, 10960-74