InterPro domain: IPR013929

General Information

  • Identifier IPR013929
  • Description RNA polymerase II-associated protein 1, C-terminal
  • Number of genes 109
  • Gene duplication stats Loading...

Abstract

Inhibition of RNA polymerase II-associated protein 1 (RPAP1) synthesis in Saccharomyces cerevisiae (Baker's yeast) results in changes in global gene expression that are similar to those caused by the loss of the RNAPII subunit Rpb11 [ 1 ]. This entry represents the C-terminal region that contains the motif GLHHH. This region is conserved from yeast to humans.


1. RPAP1, a novel human RNA polymerase II-associated protein affinity purified with recombinant wild-type and mutated polymerase subunits. Mol. Cell. Biol. 24, 7043-58

Species distribution

Gene table