InterPro domain: IPR013907

General Information

  • Number of genes 6
  • Gene duplication stats Loading...

Abstract

Repression of gene transcription is mediated by histone deacetylases containing repressor-co-repressor complexes, which are recruited to promoters of target genes via interactions with sequence-specific transcription factors. The co-repressor complex contains a core of at least seven proteins [ 1 ]. This entry represents the conserved region found in Sds3, Dep1 and BRMS1-homologue p40 proteins.


1. Identification of a novel BRMS1-homologue protein p40 as a component of the mSin3A/p33(ING1b)/HDAC1 deacetylase complex. Biochem. Biophys. Res. Commun. 323, 1216-22

Species distribution

Gene table