InterPro domain: IPR013883

General Information

  • Identifier IPR013883
  • Description Transcription factor Iwr1 domain
  • Number of genes 104
  • Gene duplication stats Loading...

Abstract

Iwr1 is involved in transcription from polymerase II promoters; it interacts with with most of the polymerase II subunits [ 1 ]. Deletion of this protein results in hypersensitivity to the K1 killer toxin [ 2 ].

This entry represents a domain found in Iwr1. This domain can also be found in SLC7A6OS and RDM4 (At2g30280). RDM4 is a regulatory factor for several RNA polymerases [ 3 ].


1. The yeast RNA polymerase II-associated factor Iwr1p is involved in the basal and regulated transcription of specific genes. J. Biol. Chem. 284, 28958-67
2. A Saccharomyces cerevisiae genome-wide mutant screen for altered sensitivity to K1 killer toxin. Genetics 163, 875-94
3. RNA-directed DNA methylation and plant development require an IWR1-type transcription factor. EMBO Rep. 11, 65-71

Species distribution

Gene table