InterPro domain: IPR013721
General Information
- Identifier IPR013721
- Description STAG
- Number of genes 123
- Gene duplication stats Loading...
Abstract
STAG domain proteins are subunits of cohesin complex - a protein complex required for sister chromatid cohesion in eukaryotes. The STAG domain is present in Schizosaccharomyces pombe (Fission yeast) mitotic cohesin Psc3, and the meiosis specific cohesin Rec11. Many organisms express a meiosis-specific STAG protein, for example, mice and humans have a meiosis specific variant called STAG3, although budding yeast does not have a meiosis specific version [ 1 ].
1. Cohesins are required for meiotic DNA breakage and recombination in Schizosaccharomyces pombe. Proc. Natl. Acad. Sci. U.S.A. 102, 10952-7
Species distribution
Gene table
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