InterPro domain: IPR013252

General Information

  • Identifier IPR013252
  • Description Kinetochore-Ndc80 subunit Spc24
  • Number of genes 7
  • Gene duplication stats Loading...

Abstract

Spc24 is a component of the evolutionarily conserved kinetochore-associated Ndc80 complex, which is implicated in several essential outer kinetochore functions, including microtubule binding and control the spindle assembly checkpoint [ 1 , 2 ].


1. The Ndc80 complex: hub of kinetochore activity. FEBS Lett. 581, 2862-9
2. The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation. J. Cell Biol. 152, 349-60

Species distribution

Gene table