InterPro domain: IPR013212

General Information

  • Identifier IPR013212
  • Description Mad3/Bub1 homology region 1
  • Number of genes 343
  • Gene duplication stats Loading...

Abstract

Proteins containing this domain are checkpoint proteins involved in cell division. This region has been shown to be essential for the binding of Bub1 and Mad3 to Cdc20 [ 1 ].


1. MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p. J. Cell Biol. 148, 871-82

Species distribution

Gene table