InterPro domain: IPR013174

General Information

  • Identifier IPR013174
  • Description Dolichol-phosphate mannosyltransferase subunit 3
  • Number of genes 126
  • Gene duplication stats Loading...
  • Associated GO terms GO:0006486  

Abstract

This family corresponds to subunit 3 of dolichol-phosphate mannosyltransferase, an enzyme which generates mannosyl donors for glycosylphosphatidylinositols, N-glycan and protein O- and C-mannosylation. DPM3 is an integral membrane protein and plays a role in stabilising the dolichol-phosphate mannosyl transferase complex [ 1 ].


1. Human dolichol-phosphate-mannose synthase consists of three subunits, DPM1, DPM2 and DPM3. EMBO J. 19, 2475-82

Species distribution

Gene table