InterPro domain: IPR013049
General Information
- Identifier IPR013049
- Description Spo11/DNA topoisomerase VI, subunit A, N-terminal
- Number of genes 354
- Gene duplication stats Loading...
- Associated GO terms GO:0003677 GO:0005524 GO:0003824 GO:0005694 GO:0006259
Abstract
This entry represents the N-terminal domain found in Spo11, a meiotic recombination protein found in eukaryotes, and in subunit A of topoisomerase VI, a type IIB topoisomerase found predominantly in archaea [ 1 , 2 ]. These two types of proteins share structural homology.
1. Structure and function of an archaeal topoisomerase VI subunit with homology to the meiotic recombination factor Spo11. EMBO J. 18, 6177-88
2. Emerging roles for plant topoisomerase VI. Chem. Biol. 10, 107-11
Species distribution
Gene table
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